Bias-Variance Tradeoff, Model Fitting

CSI 5180 - Machine Learning for Bioinformatics

Prepare

• Understanding the Bias-Variance Tradeoff by Scott Fortmann-Roe, June 2012

Participate

• slides

Further Readings

• Libbrecht and Noble (2015)
• Statnikov et al. (2004)
• Ambroise and McLachlan (2002)

References

Ambroise, Christophe, and Geoffrey J. McLachlan. 2002. “Selection bias in gene extraction on the basis of microarray gene-expression data.” Proceedings of the National Academy of Sciences 99 (10): 6562–66. https://doi.org/10.1073/pnas.102102699.

Libbrecht, Maxwell W, and William Stafford Noble. 2015. “Machine learning applications in genetics and genomics.” Nature Reviews Genetics 16 (6): 321–32. https://doi.org/10.1038/nrg3920.

Statnikov, Alexander, Constantin F. Aliferis, Ioannis Tsamardinos, Douglas Hardin, and Shawn Levy. 2004. “A comprehensive evaluation of multicategory classification methods for microarray gene expression cancer diagnosis.” Bioinformatics 21 (5): 631–43. https://doi.org/10.1093/bioinformatics/bti033.